Over 40 publications using NanoIntegris materials.
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Chemical and Biological Sensors
Graphene Electrochemistry: Fabricating Amperometric Biosensors
Application: Chemical and Biological Sensors
Citation: Dale A. C. Brownson and Craig E. Banks, Analyst (2011), 136, 10, 2084-2089.
Summary: The electrochemical sensing of hydrogen peroxide is of substantial interest to the operation of oxidase-based amperometric biosensors. We explore the fabrication of a novel and highly sensitive electro-analytical biosensor using well characterised commercially available graphene and compare and contrast responses using Nafion -graphene and -graphite modified electrodes. Interestingly we observe that graphite exhibits a superior electrochemical response due to its enhanced percentage of edge plane sites when compared to graphene. However, when Nafion, routinely used in amperometric biosensors, is introduced onto graphene and graphite modified electrodes, re-orientation occurs in both cases which is beneficial in the former and detrimental in the latter; insights into this contrasting behaviour are consequently presented providing acuity into sensor design and development where graphene is utilised in biosensors.
An Ultrasensitive and Low-Cost Graphene Sensor Based on Layer-By-Layer Nano Self-Assembly
Application: Chemical and Biological Sensors, Biomedical
Citation: Bo Zhang and Tianhong Cui, Applied Physics Letters (2011), 98, 073116.
Summary: The flexible cancer sensor based on layer-by-layer self-assembled graphene reported in this letter demonstrates features including ultrahigh sensitivity and low cost due to graphene material properties in nature, self-assembly technique, and polyethylene terephthalate substrate. According to the conductance change of self-assembled graphene, the label free and labeled graphene sensors are capable of detecting very low concentrations of prostate specific antigen down to 4 fg/ml (0.11 fM) and 0.4 pg/ml (11 fM), respectively, which are three orders of magnitude lower than carbon nanotube sensors under the same conditions of design, manufacture, and measurement.
Ultrasensitive Detection of DNA Molecules with High On/Off Single-Walled Carbon Nanotube Network
Application: Chemical and Biological Sensors
Summary: Semiconducting networks were found to be extremely sensitive to charges, which promises the electrical detection of ultralow concentrations of DNA (down to 0.1 fM, ∼100 DNA molecules).
